Pipeline

Our Pipeline of Wholly Owned Assets and Partnered Programs

We’re building a comprehensive pipeline of drug candidates that deliver on the promise of modulating RNA biology for therapeutic benefit.

Target Target Class Indication Target-to-HTS Hit to Lead Lead Op Development Candidate Partner
elF4E Protein Oncology
c-MYC RNA Oncology
Regnase-1 Protein Immuno-oncology
Multiple Programs RNA Oncology
Multiple Targets RNA Undisclosed
Status Undisclosed
Multiple Targets RNA Undisclosed
Status Undisclosed
Ribometrix lab

Where We’re Starting

Our industry-leading RNA biology and drug discovery capabilities drive our unique approach to address targets considered “undruggable” by conventional methods: we modulate the biology of mRNAs, preventing the production of disease-driving proteins. This opens a new path to targeting the drivers of cancer and other diseases.

We are focused on mRNAs of undruggable proteins and RBPs linked to specific disease phenotypes. Our industry-leading drug discovery platform enables us to leverage proprietary RNA structure determination capabilities and state-of-the-art RNA tools and technologies to directly target and modulate RNA biology.